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Wall Street's main indexes soared on Thursday with the S&P 500 and the Dow hitting intraday record highs after the Federal Reserve kicked off its monetary easing cycle with half-a-percentage point reduction and forecast more interest rate cuts were on the horizon. .N

At 1341 ET, the Dow Jones Industrial Average .DJI was up 1.47% at 42,111.47. The S&P 500 .SPX was up 1.95% at 5,727.69 and the Nasdaq Composite .IXIC was up 2.81% at 18,067.481.

The top three S&P 500 .PG.INX percentage gainers:
** Darden Restaurants DRI.N, up 8.7%
** Tesla TSLA.O, up 7.2%
** Advanced Micro Devices AMD.O, up 7%

The top three S&P 500 .PL.INX percentage losers:
** Iron Mountain IRM.N, down 3.4%
** American Tower AMT.N, down 2.8%
** Ventas VTR.N, down 2.7%

The top two NYSE .PG.N percentage gainers:
** Impact Biomedical IBO.N, up 21.8%
** Li-Cycle Holdings LICY.N, up 20.8%

The top NYSE .PL.N percentage loser:
** Healthy Choice Wellness HCWC.N, down 27.6%

The top three Nasdaq .PG.O percentage gainers:
** Garden StageGSIW.O, up 128%
** Zeo Energy ZEO.O, up 109.6%
** Telesis Bio TBIO.O, up 103.7%

The top three Nasdaq .PL.O percentage losers:
** Golden Heaven Group Holdings GDHG.O, down 32.9%
** Progyny PGNY.O, down 32.3%
** XCHG XCH.O, down 29%

** Progyny PGNY.O: down 32.3%
BUZZ - Plummets as big client plans to terminate services agreement

** Apple Inc AAPL.O: up 3.8%

** Meta Platform Inc META.O: up 3.7%

** Microsoft MSFT.O: up 1.9%

** Nvidia Corp NVDA.O: up 5.3%
BUZZ - Tech stocks lead broad rally as investors cheer Fed's jumbo rate cut

** Coinbase Global COIN.O: up 5.1%

** Bitfarms BITF.O: up 5.9%

** Microstrategy MSTR.O: up 11.6%

** Riot Platforms RIOT.O: up 1.7%
BUZZ - Crypto stocks rise after bitcoin hits three-week high

** JPMorgan Chase JPM.N: up 1.4%

** Wells Fargo WFC.N: up 3.0%

** Bank of America BAC.N: up 2.9%

** Citigroup C.N: up 4.4%
BUZZ - US big banks rise after Fed's jumbo rate cut

** America’s Car-Mart Inc CRMT.O: down 15.3%
BUZZ - Skids on pricing stock offering

** Target TGT.N: up 2.3%
BUZZ - Names new CFO; shares rise

** Rio Tinto RIO.N: up 3.6%
BUZZ - MS sees seasonal restock to bring metals & mining back into focus

** Hawaiian Electric Industries HE.N: down 8.7%
BUZZ - Drops on $250 mln stock offering plans

** Mobileye Global MBLY.O: up 16.6%
BUZZ - Rises after Intel says no plans to divest majority stake

** KeyCorp KEY.N: up 4.1%

** Regions Financial RF.N: up 2.8%

** Fifth Third Bancorp FITB.O: up 2.7%

** Banc of California BANC.N: up 3.8%
BUZZ - US regional banks rise as jumbo rate cut soothes deposit cost concerns

** Vanda Pharmaceuticals VNDA.O: down 6.0%
BUZZ - Drops after US FDA declines drug approval

** Hess Midstream HESM.N: down 2.7%
BUZZ - Falls after upsized secondary offering priced

** D R Horton DHI.N: up 1.4%

** Lennar LEN.N: up 1.9%

** Pultegroup PHM.N: up 2.4%

** Toll Brothers TOL.N: up 2.5%
BUZZ - US homebuilders rise after Fed rate cut

** Darden Restaurants DRI.N: up 8.7%
BUZZ - Jumps on Uber food-delivery partnership

** DoorDash DASH.O: up 3.6%
BUZZ - Rises as BTIG upgrades to 'buy'

** Spotify Technology SPOT.N: up 5.6%
BUZZ - Rises after Pivotal Research raises PT

** United States Steel X.N: up 2.4%
BUZZ - Shares rise on third-quarter profit forecasts

** Harley-Davidson HOG.N: up 3.6%
BUZZ - Citi raises PT on Harley-Davidson citing 'renewed Fed-driven optimism'

** Coursera COUR.N: up 8.8%
BUZZ - Jumps after BofA starts with 'buy' rating

** Trump Media & Technology Group DJT.O: down 4.2%
BUZZ - Hits new low as lock-up expiry looms

** Tandem Diabetes Care TNDM.O: up 3.8%
BUZZ - Rises as EU clears its insulin pump for use with Lilly's fast-acting insulin

** FactSet Research Systems FDS.N: up 4.4%
BUZZ - Hits 6-month high after strong Q4 results

** Edgewise Therapeutics EWTX.O: up 48.0%
BUZZ - Jumps on early data for heart disease drug

** Children's Place PLCE.O: up 11.2%
BUZZ - Up after UBS raises PT

** Exxon Mobil XOM.N: up 2.4%

** Chevron CVX.N: up 1.8%

** Baker Hughes BKR.N: up 6.5%

** Crescent Energy CRGY.N: up 4.1%
BUZZ - US energy sector rises after US Fed rate cut, Middle East worries

** American International Group AIG.N: up 1.2%
BUZZ - Up after appointing new CFO

** OceanFirst Financial OCFC.O: up 3.4%
BUZZ - Gains day after settling US redlining charges

** Galmed Pharmaceuticals GLMD.O: up 59.3%
BUZZ - Surges on plans to expand into cancer and heart disease drug development

** Helix Energy Solutions Group HLX.N: up 6.7%
BUZZ - Surges on plans to expand into cancer and heart disease drug development

The 11 major S&P 500 sectors:

(Compiled by Rajarshi Roy and Neil J Kanatt)

((Neil.JKanatt@thomsonreuters.com))