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Wall Street's main indexes were flat on Wednesday as investors stepped onto the sidelines ahead of the Federal Reserve's highly anticipated first interest rate cut in more than four years, with bets favoring a 50-basis-point reduction. .N

At 11:44 ET, the Dow Jones Industrial Average .DJI was down 0.12% at 41,555.40. The S&P 500 .SPX was down 0.15% at 5,626.23 and the Nasdaq Composite .IXIC was down 0.02% at 17,624.485.

The top three S&P 500 .PG.INX percentage gainers:
** West Pharmaceutical Services , up 4.7%
** General Motors , up 2.5%
** CH Robinson Ww , up 2.3%

The top three S&P 500 .PL.INX percentage losers:
** ResMed , down 5.1%
** Sysco , down 3%
** Albemarle , down 3%

The top three NYSE .PG.N percentage gainers:
** Bausch Health , up 9.9%
** KORE Group Holdings , up 9.2%
** Bausch + Lomb , up 7.9%

The top two NYSE .PL.N percentage losers:
** Healthy Choice Wellness , down 20.4%
** Ermenegildo Zegna , down 7.1%

The top tWO Nasdaq .PG.O percentage gainers:
** Portage Biotech , up 268.7%

The top three Nasdaq .PL.O percentage losers:
** Galmed Pharmaceuticals , down 47%
** Cibus , down 25.1%
** Allarity Therapeutics , down 22.1%

** General Mills GIS.N: up 1.0%
BUZZ - Up on signs of improving volume trends through FY25

** Intuitive Machine LUNR.O: up 54.0%
BUZZ - Jumps on $4.8 bln contract from NASA

** GE Healthcare Technologies GEHC.O: up 1.8%
BUZZ - BTIG upgrades GE Healthcare to 'buy'

** VF VFC.N: up 4.3%
BUZZ - Up after Barclays raises to 'overweight', hikes PT

** i-80 Gold IAUX.N: up 8.8%
BUZZ - Names new CEO; shares rise

** Super Micro Computer SMCI.O: up 1.2%
BUZZ - Rises after Needham initiates coverage with 'Buy'

** Cibus CBUS.O: down 25.1%
BUZZ - Slides after $12 mln stock offering

** Ambac Financial Group AMBC.N: up 5.8%
BUZZ - Hits over 1-month high after Roth MKM's upgrade

** Extra Storage Space EXR.N: up 1.6%
BUZZ - Rises on Jefferies upgrade

** Applied Therapeutics APLT.O: up 61.0%
BUZZ - Jumps as US FDA cancels panel meeting for genetic disorder drug

** Casella Waste Systems CWST.O: down 5.9%
BUZZ - Drops on $450 mln stock offering for acquisition

** Roivant Sciences ROIV.O: up 1.5%
BUZZ - Rises as Organon agrees to buy its unit for up to $1.2 billion

** United States Steel X.N: up 3.0%
BUZZ - Up on report of CFIUS delaying decision on Nippon merger

** Powerfleet AIOT.O: up 4.3%
BUZZ - Rises on Fleet Complete deal

** Civitas Resources CIVI.N: down 0.7%
BUZZ - J. P.Morgan starts coverage of energy producer Civitas with 'overweight' rating

** ResMed RMD.N: down 5.1%
BUZZ - Falls as Wolfe Research downgrades to 'underperform' on GLP-1 risks

** NMI Holding NMIH.O: up 1.6%
BUZZ - Rises after RBC upgrades to 'outperform'

** Cencora COR.N: down 2.2%
BUZZ - Drops after report of drug distributor paying $75 million in ransom

** Vivos Therapeutics VVOS.O: up 35.2%
BUZZ - Rises on FDA approval for pediatric sleep apnea device

** Trump Media & Technology Group DJT.O: down 4.3%
BUZZ - Plumbs new lows as lock-up expiration approaches

** Gladstone Investment GAIN.O: up 4.0%
BUZZ - Gains on supplemental cash distribution to stockholders

The 11 major S&P 500 sectors:

(Compiled by Rajarshi Roy and Neil J Kanatt)

((Neil.JKanatt@thomsonreuters.com))