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Wall Street's main indexes fell on Wednesday after latest inflation hit expectations of a bigger interest rate cut by the Federal Reserve, while odds of Democrat Kamala Harris winning the U.S. presidency rose following a televised debate. .N

At 14:04 ET, the Dow Jones Industrial Average .DJI was down 0.3% to 40,628.2. The S&P 500 .SPX was up 0.26% at 5,509.68 and the Nasdaq Composite .IXIC was up 1.17% at 17,225.631.

The top three S&P 500 .PG.INX percentage gainers:
** First Solar , up 12.1%
** Albemarle , up 11%
** The AES Corporation , up 7.1%

The top three S&P 500 .PL.INX percentage losers:
** Humana Inc , down 5.2%
** Conagra Brands , down 4.5%
** American Airlines Group , down 4%

The top two NYSE .PG.N percentage gainers:
** Mesabi Trust , up 22.2%
** Oscar Health , up 17%

The top two NYSE .PL.N percentage losers:
** Torrid Holdings , down 23.4%
** Rentokil Initial , down 20.6%

The top three Nasdaq .PG.O percentage gainers:
** Children's Place , up 104.5%
** PureCycle Technologies , up 38.4%
** Petco Health and Wellness Company , up 34.2%

The top three Nasdaq .PL.O percentage losers:
** Laser Photonics Corp , down 41.1%
** Synaptogenix , down 17.5%
** Relay Therapeutics , down 17.4%

** GameStop Corp GME.N: down 15.5%
BUZZ - Slips on Q2 rev decline, files 20 mln stock offering

** Trump Media & Technology Group Corp DJT.O: down 12.8%
BUZZ - Slides as odds of Trump win dip following debate

** Bank of America Corp BAC.N: down 1.7%
BUZZ - Dips as Buffett's Berkshire extends selling spree

** Albemarle Corp ALB.N: up 11.0%

** Arcadium Lithium PLC ALTM.N: up 14.2%

** Piedmont Lithium Inc PLL.O: up 6.1%

** Lithium Americas Corp LAC.N: up 6.3%
BUZZ - Lithium miners gain after China's CATL says it will adjust production

** Relay Therapeutics Inc RLAY.O: down 17.4%
BUZZ - Drops on deep-discounted $200 mln equity offering

** Cantaloupe Inc CTLP.O: down 4.1%
BUZZ - Slips on lackluster Q4 results

** Dave & Buster's Entertainment Inc PLAY.O: up 2.3%
BUZZ - Jumps after Q2 profit beat

** Maxeon Solar Technologies Ltd MAXN.O: up 11.0%

** Jinkosolar Holding Co Ltd JKS.N: up 2.0%

** Enphase Energy Inc ENPH.O: up 3.7%

** Canadian Solar Inc CSIQ.O: up 9.5%
BUZZ - Solar stocks gain as odds of Harris win rise after presidential debate

** Designer Brands Inc DBI.N: down 13.9%
BUZZ - Tumbles on cutting annual profit forecast

** Orion Group Holdings Inc ORN.N: down 9.3%
BUZZ - Tumbles on pricing stock offering

** GEO Group Inc GEO.N: down 7.5%

** CoreCivic Inc CXW.N: down 4.6%
BUZZ - Falls after Harris-Trump debate

** Manchester United PLC MANU.N: down 5.9%
BUZZ - Falls on posting bigger annual loss

** BridgeBio Pharma Inc BBIO.O: down 2.7%
BUZZ - To stop development of genetic disorder therapy, shares fall

** Children's Place Inc PLCE.O: up 104.5%
BUZZ - Soars as lower expenses boost Q2 profit

** Centrus Energy Corp LEU.N: up 10.0%
BUZZ - Up on signing supply commitment with Korean firm

** Viking Therapeutics Inc VKTX.O: up 9.3%
BUZZ - Surges after JPM's 'overweight' rating

** Petco Health and Wellness Company Inc WOOF.O: up 34.2%
BUZZ - Reverses course after brokerages lift PT

** Vera Bradley Inc VRA.O: down 7.2%
BUZZ - Falls on lowered annual forecasts, Q2 sales miss

** Williams-Sonoma Inc WSM.N: up 2.4%
BUZZ - Rises after Jefferies upgrades to "buy"

** Applied DNA Sciences Inc APDN.O: up 27.3%
BUZZ - Rises after expanding mpox testing service

** Uranium Energy Corp UEC.N: up 9.9%

** Energy Fuels Inc UUUU.N: up 7.7%

** Ur-Energy Inc URG.N: up 6.8%

** NexGen Energy Ltd NXE.N: up 4.4%
BUZZ - Uranium miners rise after Putin says Russia should limit exports

** UnitedHealth Group Inc UNH.N: down 1.6%

** CVS Health Corp CVS.N: down 2.4%

** Humana Inc HUM.N: down 5.2%
BUZZ - Health insurers fall after bets on Harris win rise after debate

** Torrid Holdings Inc CURV.N: down 23.4%
BUZZ - Shares frigid as PE sponsor, CEO to cut stakes

** BurgerFi International Inc BFI.O: down 19.0%
BUZZ - Down after company files for bankruptcy protection

** AES Corp AES.N: up 7.1%
BUZZ - Rises as Jefferies initiates coverage with 'buy' rating

** Phillips 66 PSX.N: down 1.5%
BUZZ - TD Cowen sees renewable fuels earnings weakness for Phillips 66 in Q3; cuts PT

The 11 major S&P 500 sectors:

(Compiled by Rajarshi Roy and Puyaan Singh in Bengaluru)

((Rajarshi.Roy@thomsonreuters.com))