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Wall Street's main indexes advanced on Wednesday, aided by gains in megacap stocks and a dovish turn by Japan's top policymaker after a surprise interest rate hike last week that partly sparked heavy volatility in global markets. .N

At 14:35 ET, the Dow Jones Industrial Average .DJI was down 0.52% at 38,793.6. The S&P 500 .SPX was down 0.53% at 5,212.5 and the Nasdaq Composite .IXIC was down 0.77% at 16,240.061.

The top three S&P 500 .PG.INX percentage gainers:
** Fortinet , up 26.8 %
** Axon Enterprise , up 16.5 %
** Global Payments , up 7.6 %

The top three S&P 500 .PL.INX percentage losers:
** Super Micro Computer Ord , down 20.1 %
** Airbnb Inc Ord , down 14.5 %
** Charles River Laboratories , down 12.9 %

The top three NYSE .PG.N percentage gainers:
** Lumen Technology Ord , up 28.6 %
** Revolve Group Inc , up 28.5 %
** Rayonier Inc , up 26.4 %

The top three NYSE .PL.N percentage losers:
** Nevro Corp , down 44.4 %
** Emergent Biosolution , down 43.7 %
** Actinium Pharmaceuticals , down 26.9 %

The top three Nasdaq .PG.O percentage gainers:
** G1 Therapeutics Inc , up 66.1 %
** Petiq Inc A , up 47.8 %
** Salarius Pharmaceutical , up 39.8 %

The top three Nasdaq .PL.O percentage losers:
** Tals Biomedical Ord , down 49.7 %
** ODP Corporat Ord , down 33.7 %
** Superior Group Companies , down 30.6 %

** Tripadvisor Inc TRIP.O: down 15.1%

** Airbnb Inc ABNB.O: down 14.5%
BUZZ - Slump after results as economic worries weigh on demand

** Fortinet Inc FTNT.O: up 26.8%
BUZZ - Set for best day after co hikes FY24 revenue forecast

** Amgen Inc AMGN.O: down 6.5%
BUZZ - Falls as Q2 profit slips

** NextDecade Corp NEXT.O: down 16.8%
BUZZ - Down as US court revokes Rio Grande project permit

** Progyny Inc PGNY.O: down 19.7%
BUZZ - Slides after trimming annual profit and revenue forecasts

** Lyft Inc LYFT.O: down 15.2%
BUZZ - Down after downbeat Q3 profit, gross booking forecasts

** CVS Health Corp CVS.N: down 2.0%
BUZZ - Falls on annual profit forecast cut

** Walt Disney Co DIS.N: down 3.1%
BUZZ - Falls on profit drop at key parks business

** Hilton Worldwide Holdings Inc HLT.N: down 1.3%
BUZZ - Dips after cutting FY RevPAR forecast

** SpringWorks Therapeutics Inc SWTX.O: up 2.9%
BUZZ - Rises on Q2 revenue beat

** Emergent BioSolutions Inc EBS.N: down 43.7%
BUZZ - Plunges on wider-than-expected Q2 loss

** Upstart Holdings Inc UPST.O: up 40.6%
BUZZ - Eyes best day in over three years after upbeat Q3 revenue forecast

** G1 Therapeutics Inc GTHX.O: up 66.1%
BUZZ - Jumps on $405 mln buyout from Pharmacosmos

** Suncor Energy Inc SU.N: up 5.3%
BUZZ - TD Cowen raises Suncor Energy to 'buy' from 'hold'

** Global Payments Inc GPN.N: up 7.6%
BUZZ - Up after Q2 profit beat

** Charles River Laboratories International Inc CRL.N:down 12.9%
BUZZ - Falls after cutting yearly profit, revenue forecast, flags soft demand

** Trex Co Inc TREX.N: down 21.2%
BUZZ - Tumbles on Q2 rev miss, downbeat FY rev forecast

** Nevro Corp NVRO.N: down 44.4%
BUZZ - Dips after lowering 2024 revenue forecast

** Cryoport Inc CYRX.O: down 3.9%
BUZZ - Falls on lowering annual revenue forecast

** Shopify Inc SHOP.N: up 19.2%
BUZZ - Jumps on Q2 results beat, upbeat forecast

** RealReal Inc REAL.O: down 21.1%
BUZZ - Slides after 2024 forecast cut

** Aurora Cannabis Inc ACB.O: up 7.0%
BUZZ - Rises on strong Q1 results

** Emerson Electric Co EMR.N: down 7.1%
BUZZ - Falls after Q3 revenue miss

** Illumina Inc ILMN.O: up 2.1%
BUZZ - Up after Q2 results; Citigroup raises PT

** Icahn Enterprises LP IEP.O: down 4.5%
BUZZ - Down after co reports wider Q2 loss

** Veracyte Inc VCYT.O: up 23.3%
BUZZ - Rises after FY revenue forecast uplift

** Rockwell Automation Inc ROK.N: down 1.2%
BUZZ - Slips on cutting annual profit forecast

** New York Times Co NYT.N: up 3.5%
BUZZ - Jumps on upbeat second-quarter results

** Inspire Medical Systems Inc INSP.N: up 23.2%
BUZZ - Gains after raising 2024 profit outlook

** Chevron Corp CVX.N: flat

** Exxon Mobi Corp XOM.N: up 1.5%

** APA Corp APA.O: up 0.6%

** Baker Hughes Co BKR.O: up 0.9%
BUZZ - Energy firms rise on Middle East tensions

** PetIQ Inc PETQ.O: up 47.8%
BUZZ - Surges on $1.5 bln take-private deal with Bansk Group

** Abbott Laboratories ABT.N: up 0.4%

** Medtronic PLC MDT.N: up 0.2%
BUZZ - Rise on glucose monitoring partnership

** 2seventy Bio Inc TSVT.O: up 11.2%
BUZZ - Rises on Q2 profit

** Axon Enterprise Inc AXON.O: up 16.4%
BUZZ - Surges on Q2 beat, outlook lift

** Reddit Inc RDDT.N: down 7.2%
BUZZ - Falls after upbeat outlook as IPO lock-up expiration looms

** Tandem Diabetes Care Inc TNDM.O: down 12.6%

** Insulet Corp PODD.O: down 2.0%

** Dexcom Inc DXCM.O: down 7.3%
BUZZ - Some diabetes device makers fall after Abbott, Medtronic glucose monitoring partnership

** Super Micro Computer Inc SMCI.O: down 20.1%
BUZZ - Hits six-month low on gross margin worries; set to cede S&P 500 top performer to Nvidia

** Maplebear Inc CART.O: up 3.4%
BUZZ - Rises after company posts Q3 key metrics above estimates

** Bio-Techne Corp TECH.O: down 7.5%
BUZZ - Falls on revenue miss

** Lumen Technologies Inc LUMN.N: up 28.6%
BUZZ - Extends AI-fueled surge after rosy cash flow outlook, Wall Street PT hikes

** Robinhood Markets Inc HOOD.O: down 1.6%
BUZZ - Flat ahead of report; analysts eye meme-stock bump

The 11 major S&P 500 sectors:

(Compiled by Rajarshi Roy and Jaiveer Shekhawat)

((jaiveersingh.shekhawat@thomsonreuters.com))