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Wall Street's main indexes edged higher on Friday as gains in megacap stocks outweighed pressure from a stronger-than-expected jobs report that tempered expectations of rapid interest rate cuts this year. .N

At 10:46 a.m. ET, the Dow Jones Industrial Average .DJI was up 0.34% at 37,566.28. The S&P 500 .SPX was up 0.65% at 4,719.16 and the Nasdaq Composite .IXIC was up 0.73% at 14,616.381.

The top three S&P 500 .PG.INX percentage gainers:
** Moderna MRNA.O, up 5.7%
** Catalent CTLT.N, up 4.8%
** Citizens Financial Group CFG.N, up 3.6%

The top three S&P 500 .PL.INX percentage losers:
** Humana HUM.N, down 2.3%
** Huntington Ingalls Industries HII.N, down 1.6%
** MSCI MSCI.N, down 1.4%

The top three NYSE .PG.N percentage gainers:
** YieldMax MRNA Option Income Strategy ETF MRNY.N, up 25%
** Pinstripes Holdings PNST.N, up 16%
** Wheels Up Experience UP.N, up 12.1%

The top three NYSE .PL.N percentage losers:
** Agilon health AGL.N, down 35.3%
** Medical Properties Trust MPW.N, down 30.5%
** 2x Long VIX Futures ETF UVIX.N, down 7.8%

The top two Nasdaq .PG.O percentage gainers:
** Ainos Inc AIMD.O, up 99.5%
** Revelstone Capital Acquisition RCAC.O, up 88.7%

The top three Nasdaq .PL.O percentage losers:
** Applied Therapeutics APLT.O, down 34.6%
** AngioDynamics ANGO.O, down 21.2%
** Regencell Bioscience Holdings RGC.O, down 21%

** Medical Properties Trust MPW.N: down 30.5%
BUZZ - Plunges after plan to recover uncollected rent

** Palantir Technologies PLTR.N: down 2.1%
BUZZ - Falls after Jefferies downgrades to 'underperform'

** Applied Therapeutics APLT.O: down 34.6%
BUZZ - Falls after heart drug disappoints in late-stage trial

** Voyager Therapeutics VYGR.O: down 20.7%
BUZZ - Slides as $100 mln stock offering priced

** Dyne Therapeutics DYN.O: down 9.4%
BUZZ - Dips after upsized $300 mln stock offering

** Theravance Biopharma TBPH.O: down 5.8%
BUZZ - Tumbles as lung disease drug fails to meet main goal

** Allogene Therapeutics ALLO.O: down 16.1%
BUZZ - Falls on de-prioritizing two cell therapy studies

** AngioDynamics ANGO.O: down 21.2%
BUZZ - Down on wider loss forecast

** Catalyst Pharmaceuticals CPRX.O: down 14.5%
BUZZ - Falls on pricing $150 mln stock deal

** D R Horton DHI.N: up 1.5%

** Toll Brothers TOL.N: up 1.8%

** KB Home KBH.N: up 1.9%
BUZZ - KBW raises PTs for US homebuilders

** Eagle Bulk Shipping EGLE.N: down 1.6%

** Genco Shipping & Trading GNK.N: down 1.1%

** Golden Ocean Group GOGL.O: down 0.9%
BUZZ - BTIG says dry bulk shipping firms on troubled waters in 2024

** Conagra Brands CAG.N: down 0.5%
BUZZ - Edges lower after brokerages cut PT

** Agilon Health Inc AGL.N: down 35.3%
BUZZ - Slumps on 2023 revenue forecast cut

** McDonald's Corp MCD.N: down 1.2%
BUZZ - Edges lower after Oppenheimer downgrades to 'perform'

** Chevron CVX.N: up 0.4%

** Exxon Mobil XOM.N: up 0.9%

** Devon Energy DVN.N: up 0.4%

** Occidental Petroleum OXY.N: up 0.5%
BUZZ - Oil companies rise as Middle East tensions prevail

** Eli Lilly and Co LLY.N: up 0.4%
BUZZ - Leerink confident about success of Lilly's obesity drug in other trials in 2024

** Peloton Interactive PTON.O: up 16.7%
BUZZ - Rises after exclusive partnership with TikTok

** Constellation Brands STZ.N: up 3.5%
BUZZ - Up as strong beer margins drive Q3 profit beat

** Elanco Animal Health ELAN.N: up 9.3%
BUZZ - Rises as Stifel upgrades to 'buy' and raises PT

** Kymera Therapeutics KYMR.O: up 2.4%
BUZZ - Rises after upsized stock offering, JPM upgrade

** CVS Health Corp CVS.N: up 1.9%
BUZZ - Gains after raising expectations for 2024 Medicare Advantage enrollment

** Precision Drilling Corp PDS.N: up 3.1%
BUZZ - Rises on meeting debt reduction target for 2023

The 11 major S&P 500 sectors:

(Compiled by Rajarshi Roy and Kabir Dweit)

((Rajarshi.Roy@thomsonreuters.com))