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U.S. stock indexes fell on Wednesday, as investors locked in profits after a strong 2023 and awaited the Federal Reserve's December meeting minutes that could offer hints on its interest rate path. .N

At 10:46 ET, the Dow Jones Industrial Average .DJI was down 0.80% at 37,413.84. The S&P 500 .SPX was down 0.80% at 4,704.77 and the Nasdaq Composite .IXIC was down 1.03% at 14,614.38.

The top three S&P 500 .PG.INX percentage gainers:
** Eli Lilly , up 3%
** Marathon Petroleum , up 2.9%
** Arch Capital Group , up 2.5%

The top three S&P 500 .PL.INX percentage losers:
** Enphase Enrgy , down 8.8%
** Align Tech , down 6.9%
** Albemarle , down 6.7%

The top three NYSE .PG.N percentage gainers:
** TDCX , up 31.7%
** China Green Agriculture , up 16.8%
** Bright Health Group , up 16.6%

The top two NYSE .PL.N percentage losers:
** Banyan Acquisition , down 32.5%
** Altisource Asset Management , down 21.9%


The top three Nasdaq .PG.O percentage gainers:
** NexImmune , up 224.2%
** Sidus Space , up 65.4%
** Sigma Additive Solutions , up 46.2%

The top three Nasdaq .PL.O percentage losers:
** Esperion Therapeutics , down 27.1%
** TC BioPharm , down 22.8%
** Peraso , down 22.2%

** SoFi Technologies SOFI.O: down 14.0%
BUZZ - Falls as KBW turns bearish after stock's recent run

** Dyne Therapeutics DYN.O: up 10.6%
BUZZ - Jumps on positive data for muscular disorder drugs

** Agios Pharmaceuticals AGIO.O: up 3.4%
BUZZ - Rises as blood disorder drug meets late-stage study goals

** Regeneron Pharmaceuticals REGN.O: up 1.0%
BUZZ - Leerink sees increased sales for Regeneron's eye drug, raises PT - Reuters

** Coinbase Global COIN.O: down 4.5%

** Bitfarms BITF.O: down 4.9%

** Riot Platforms RIOT.O: down 5.7%

** Marathon Digital Holdings MARA.O: down 2.9%
BUZZ - Crypto stocks slide as bitcoin comes off 21-month high

** Merck & Co MRK.N: up 1.7%
BUZZ - Citi picks Merck as its preferred pharma stock

** ABVC BioPharma ABVC.O: up 53.3%
BUZZ - Up on receiving $460 mln worth shares under licensing deal

** Xponential Fitness XPOF.N: down 6.8%
BUZZ - Falls after Piper Sandler downgrades to ''

** Newmont Corp NEM.N: down 3.2%

** Barrick Gold Corp GOLD.N: down 2.4%

** AngloGold Ashanti Ltd AU.N: down 2.0%

** Harmony Gold Mining Co Ltd HMY.N: down 2.3%
BUZZ - Gold miners slip on stronger dollar

** SentinelOne S.N: down 5.1%
BUZZ - To acquire PingSafe, shares drop

** Pure Storage PSTG.N: up 5.7%
BUZZ - Rises after inclusion in S&P mid-cap index, Stifel PT raise

** Pfizer PFE.N: up 0.3%
BUZZ - Up on Canada approval for bleeding disorder gene therapy

** Suncor Energy SU.N: up 4.4%
BUZZ - Rises after flagging second-highest output in Q4

** Southern First Bancshares SFST.O: up 3.3%
BUZZ - Rises after Piper Sandler upgrades to 'overweight'

** Sarepta Therapeutics SRPT.O: down 2.6%
BUZZ - Down after Dyne's drug trial for muscle disorder shows better result

The 11 major S&P 500 sectors:

(Compiled by Rajarshi Roy and Kabir Dweit)

((Rajarshi.Roy@thomsonreuters.com))